Developers of OER courses in the sciences are challenged by how to provide relevant, open laboratory content to students. The presenter will share how he overcame that challenge by creating a fully online OER version of BIO 100IN- Biological Concepts. He will share how he first altered an Open Stax textbook to include regional content, and how he created a series of open labs where students utilize common household items and processes to conduct in-home experiments. BIO 100IN is one course in the online, OER AA Liberal Arts degree pathway PCC faculty and staff are completing as an Achieving the Dream grantee.